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1

An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries

Adams, Felix F., Heckl, Dirk, Hoffmann, Thomas, Talbot, Steven R., Kloos, Arnold, Thol, Felicitas, Heuser, Michael, Zuber, Johannes, Schambach, Axel, Schwarzer, Adrian

Journal:

Year:

2017

Language:

english

File:

PDF, 14.81 MB

english, 2017

2

Cost-effectiveness of methods in personalized medicine. Results of a decision-analytic model in patients with acute myeloid leukemia with normal karyotype

Hörster, Laura, Schlenk, Richard F., Stadler, Michael, Gabriel, Maria, Thol, Felicitas, Schildmann, Jan, Vollmann, Jochen, Rochau, Ursula, Sroczynski, Gaby, Wasem, Jürgen, Ganser, Arnold, Port, Matthi

Journal:

Leukemia Research

Year:

2017

Language:

english

File:

PDF, 475 KB

english, 2017

3

Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial)

Krauter, Jürgen, Fiedler, Walter, Schlenk, Richard F., Paschka, Peter, Thol, Felicitas, Lübbert, Michael, Wattad, Mohammed, Verbeek, Mareike, Könecke, Christian, Neuhaus, Barbara, Papkalla, Armin, Keb

Journal:

British Journal of Haematology

Year:

2018

Language:

english

File:

PDF, 203 KB

english, 2018

4

Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate

Constantin Bode, Sven-Christian Sensken, Ulrike Peest, Gernot Beutel, Felicitas Thol, Bodo Levkau, Zaiguo Li, Robert Bittman, Tao Huang, Markus Tölle, Markus van der Giet, Markus H. Gräler

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 467 KB

english, 2010

5

To bleed or not to bleed: What is the factor?

Felicitas Thol, Cornelius Cornell, Gabriele Popp

Journal:

Journal of Hospital Medicine

Year:

2009

Language:

english

File:

PDF, 89 KB

english, 2009

6

Genetic changes of miR-182 G106A: rather a polymorphism than a somatic mutation

Frederik Damm, Birgit Markus, Felicitas Thol, Michael Heuser, Arnold Ganser, Jürgen Krauter

Journal:

Annals of Hematology

Year:

2011

Language:

english

File:

PDF, 221 KB

english, 2011

7

Therapeutischer Einsatz von Erythropoetin in der Dermatoonkologie

Imke Satzger, Florian Schenck, Felicitas Thol, Arnold Ganser, Alexander Kapp, Ralf Gutzmer

Journal:

JDDG: Journal der Deutschen Dermatologischen Gesellschaft

Year:

2007

Language:

german

File:

PDF, 159 KB

german, 2007

8

Therapeutic use of erythropoietin in dermatooncology

Imke Satzger, Florian Schenck, Felicitas Thol, Arnold Ganser, Alexander Kapp, Ralf Gutzmer

Journal:

JDDG: Journal der Deutschen Dermatologischen Gesellschaft

Year:

2007

Language:

english

File:

PDF, 474 KB

english, 2007

9

Prognostic significance of combinedMN1,ERG,BAALC, andEVI1(MEBE) expression in patients with myelodysplastic syndromes

Thol, Felicitas, Yun, Haiyang, Sonntag, Ann-Kathrin, Damm, Frederik, Weissinger, Eva M., Krauter, Jürgen, Wagner, Katharina, Morgan, Michael, Wichmann, Martin, Göhring, Gudrun, Bug, Gesine, Ottmann, O

Journal:

Annals of Hematology

Year:

2012

Language:

english

File:

PDF, 545 KB

english, 2012

10

Next-generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3-ITD or NPM1 mutations

Felicitas Thol, Britta Kölking, Frederik Damm, Katarina Reinhardt, Jan-Henning Klusmann, Dirk Reinhardt, Nils von Neuhoff, Martijn H. Brugman, Brigitte Schlegelberger, Sebastian Suerbaum, Jürgen Kraut

Journal:

Genes, Chromosomes and Cancer

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

11

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas Thol, Arnold Ganser

Journal:

Frontiers of Medicine

Year:

2010

Language:

english

File:

PDF, 126 KB

english, 2010

12

ID1 expression associates with other molecular markers and is not an independent prognostic factor in cytogenetically normal acute myeloid leukaemia

Frederik Damm, Katharina Wagner, Kerstin Görlich, Michael Morgan, Felicitas Thol, Haiyang Yun, Ruud Delwel, Peter J. M. Valk, Bob Löwenberg, Michael Heuser, Arnold Ganser, Jürgen Krauter

Journal:

British Journal of Haematology

Year:

2012

Language:

english

File:

PDF, 247 KB

english, 2012

13

Update on cytogenetic and molecular changes in myelodysplastic syndromes

Schlegelberger, Brigitte, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael

Journal:

Leukemia and Lymphoma

Year:

2012

Language:

english

File:

PDF, 315 KB

english, 2012

14

Prognostic significance of expression levels of stem cell regulatorsMSI2andNUMBin acute myeloid leukemia

Felicitas Thol, Claudia Winschel, Ann-Kathrin Sonntag…

Journal:

Annals of Hematology

Year:

2013

Language:

english

File:

PDF, 282 KB

english, 2013

15

Individualisierte Medizin in der Diagnostik und prognostischen Einschätzung in der akuten myeloischen Leukämie mit normalem Karyotyp bei Erwachsenen unter 65 Jahren: eine systematische Literaturrecherche und Metaanalyse zu FLT3-ITD

PD Dr. med. Matthias Port, Miriam Böttcher, Dr. med. Felicitas Thol…

Journal:

Ethik in der Medizin

Year:

2013

File:

PDF, 572 KB

2013

16

Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid leukemia

Bug, Gesine, Koschmieder, Steffen, Krauter, Juergen, Heuser, Michael, Thol, Felicitas, Wiebe, Stefanie, Hofmann, Wolf-Karsten, Klein, Stefan A., Wegener, Gerd, GÃ¶hring, Gudrun, Heit, Wolfgang, Hoelze

Journal:

Annals of Hematology

Year:

2014

Language:

english

File:

PDF, 343 KB

english, 2014

17

Lack of noncanonicalRASmutations in cytogenetically normal acute myeloid leukemia

Reuter, Christoph W. M., Krauter, Jürgen, Onono, Fredrick O., Bunke, Tania, Damm, Frederik, Thol, Felicitas, Wagner, Katharina, Göhring, Gudrun, Schlegelberger, Brigitte, Heuser, Michael, Ganser, Arno

Journal:

Annals of Hematology

Year:

2014

Language:

english

File:

PDF, 261 KB

english, 2014

18

TET2 mutations in cytogenetically normal acute myeloid leukemia: Clinical implications and evolutionary patterns

Damm, Frederik, Markus, Birgit, Thol, Felicitas, Morgan, Michael, Göhring, Gudrun, Schlegelberger, Brigitte, Krauter, Jürgen, Heuser, Michael, Bernard, Olivier A., Ganser, Arnold

Journal:

Genes, Chromosomes and Cancer

Year:

2014

Language:

english

File:

PDF, 278 KB

english, 2014

19

Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

Madan, Vikas, Kanojia, Deepika, Li, Jia, Okamoto, Ryoko, Sato-Otsubo, Aiko, Kohlmann, Alexander, Sanada, Masashi, Grossmann, Vera, Sundaresan, Janani, Shiraishi, Yuichi, Miyano, Satoru, Thol, Felicita

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

20

NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia

Morgan, Michael A., Markus, Birgit, Hermkens, Malou, Damm, Frederik, Reinhardt, Dirk, Zimmermann, Martin, Thol, Felicitas, Bunke, Tania, Bogoeva, Dessislava, Reuter, Christoph W. M., de Haas, Valerie,

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 209 KB

english, 2013

21

A phase I/II study of sunitinib and intensive chemotherapy in patients over 60 years of age with acute myeloid leukaemia and activating FLT3 mutations

Fiedler, Walter, Kayser, Sabine, Kebenko, Maxim, Janning, Melanie, Krauter, Jürgen, Schittenhelm, Marcus, Götze, Katharina, Weber, Daniela, Göhring, Gudrun, Teleanu, Veronica, Thol, Felicitas, Heuser,

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 171 KB

english, 2015

22

Gemtuzumab ozogamicin in acute myeloid leukemia revisited

Thol, Felicitas, Schlenk, Richard F

Journal:

Expert Opinion on Biological Therapy

Year:

2014

Language:

english

File:

PDF, 543 KB

english, 2014

23

Updated definition of cure in adult patients with non-APL acute myeloid leukemia

Tamamyan, Gevorg, Döhner, Konstanze, Borthakur, Gautham, Paschka, Peter, Ravandi, Farhad, Gaidzik, Verena I., Cortes, Jorge, Döhner, Hartmut, Garcia-Manero, Guillermo, Thol, Felicitas, Jabbour, Elias,

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2015

Language:

english

File:

PDF, 70 KB

english, 2015

24

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Papaemmanuil, Elli, Gerstung, Moritz, Bullinger, Lars, Gaidzik, Verena I., Paschka, Peter, Roberts, Nicola D., Potter, Nicola E., Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Gundem, Gunes, Van L

Journal:

New England Journal of Medicine

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

25

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators

Qiu, Jinsong, Zhou, Bing, Thol, Felicitas, Zhou, Yu, Chen, Liang, Shao, Changwei, DeBoever, Christopher, Hou, Jiayi, Li, Hairi, Chaturvedi, Anuhar, Ganser, Arnold, Bejar, Rafael, Zhang, Dong-Er, Fu, X

Journal:

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

26

A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl

Göhring, Gudrun, Thomay, Kathrin, Schmidt, Gunnar, Ripperger, Tim, Xu, Michael, Wittner, Nicole, Chao, Mwe Mwe, Baumann, Irith, Niewisch, Marena, Reinhardt, Dirk, Klingebiel, Thomas, Thol, Felicitas,

Journal:

Leukemia and Lymphoma

Year:

2016

Language:

english

File:

PDF, 765 KB

english, 2016

27

Precision oncology for acute myeloid leukemia using a knowledge bank approach

Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 2.03 MB

english, 2017

28

The hypomorphicTERTA1062T variant is associated with increased treatment-related toxicity in acute myeloid leukemia

Both, Anna, Krauter, Jürgen, Damm, Frederik, Thol, Felicitas, Göhring, Gudrun, Heuser, Michael, Ottmann, Oliver, Lübbert, Michael, Wattad, Mohammed, Kanz, Lothar, Schlimok, Günter, Raghavachar, Aruna,

Journal:

Annals of Hematology

Year:

2017

Language:

english

File:

PDF, 485 KB

english, 2017

29

Epigenetics in MDS

Heuser, Michael, Yun, Haiyang, Thol, Felicitas

Journal:

Seminars in Cancer Biology

Year:

2017

Language:

english

File:

PDF, 831 KB

english, 2017

30

Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype

Rücker, Frank G., Dolnik, Anna, Blätte, Tamara J., Teleanu, Veronica, Ernst, Aurélie, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

Journal:

Year:

2017

Language:

english

File:

PDF, 365 KB

english, 2017

31

Growth factor independence 1b. A key player in the genesis and maintenance of acute myeloid leukaemia and myelodysplastic syndrome

Thivakaran, Aniththa, Botezatu, Lacramiora, Hönes, Judith M., Schütte, Judith, Vassen, Lothar, Al-Matary, Yahya S., Patnana, Pradeep, Zeller, Amos, Heuser, Michael, Thol, Felicitas, Gabdoulline, Razif

Journal:

Year:

2018

Language:

english

File:

PDF, 4.27 MB

english, 2018

32

Can we forecast induction failure in acute myeloid leukemia?

Thol, Felicitas

Journal:

Year:

2018

Language:

english

File:

PDF, 134 KB

english, 2018

33

Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia—results of the AMLSG 11-08 trial

Paschka, Peter, Schlenk, Richard F, Weber, Daniela, Benner, Axel, Bullinger, Lars, Heuser, Michael, Gaidzik, Verena I, Thol, Felicitas, Agrawal, Mridul, Teleanu, Veronica, Lübbert, Michael, Fiedler, W

Journal:

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

34

When Childbirth Causes Reversed Hemodialysis and Renal Failure

Thol, Felicitas R., Popp, Gabriele

Journal:

Southern Medical Journal

Year:

2009

Language:

english

File:

PDF, 368 KB

english, 2009

35

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option

Stamm, Hauke, Klingler, Felix, Grossjohann, Eva-Maria, Muschhammer, Jana, Vettorazzi, Eik, Heuser, Michael, Mock, Ulrike, Thol, Felicitas, Vohwinkel, Gabi, Latuske, Emily, Bokemeyer, Carsten, Kischel,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

36

ASXL1/EZH2 mutations promote clonal expansion of neoplastic HSC and impair erythropoiesis in PMF

Triviai, Ioanna, Zeschke, Silke, Rentel, Jan, Spanakis, Marios, Scherer, Theo, Gabdoulline, Razif, Panagiota, Victoria, Thol, Felicitas, Heuser, Michael, Stocking, Carol, Kröger, Nicolaus

Journal:

Year:

2018

Language:

english

File:

PDF, 2.38 MB

english, 2018

37

Clonal Hematopoiesis of Indeterminate Potential

Heuser, Michael, Thol, Felicitas, Ganser, Arnold

Journal:

Deutsches "{A}rzteblatt international

Year:

2016

Language:

english

File:

PDF, 220 KB

english, 2016

38

Measurable residual disease (MRD) monitoring by NGS before allogeneic hematopoietic cell transplantation in AML

Thol, Felicitas, Gabdoulline, Razif, Liebich, Alessandro, Klement, Piroska, Schiller, Johannes, Kandziora, Christian, Hambach, Lothar, Stadler, Michael, Koenecke, Christian, Flintrop, Madita, Pankratz

Journal:

Year:

2018

Language:

english

File:

PDF, 740 KB

english, 2018

39

Routes of Clonal Evolution into Complex Karyotypes in Myelodysplastic Syndrome Patients with 5q Deletion

Feurstein, Simone, Thomay, Kathrin, Hofmann, Winfried, Buesche, Guntram, Kreipe, Hans, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Schlegelberger, Brigitte, Göhring, Gudrun

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

40

Comprehensive clinical-molecular transplant scoring system for myelofibrosis undergoing stem cell transplantation

Gagelmann, Nico, Ditschkowski, Markus, Bogdanov, Rashit, Bredin, Swan, Robin, Marie, Cassinat, Bruno, Shahswar, Rabia, Thol, Felicitas, Heuser, Michael, Socié, Gerard, Beelen, Dietrich, Triviai, Ioann

Journal:

Year:

2019

Language:

english

File:

PDF, 299 KB

english, 2019

41

Safety and efficacy of oral panobinostat plus chemotherapy in patients aged 65 years or younger with high-risk acute myeloid leukemia

DeAngelo, Daniel J., Walker, Alison R., Schlenk, Richard F., Sierra, Jorge, Medeiros, Bruno C., Ocio, Enrique M., Röllig, Christoph, Strickland, Stephen A., Thol, Felicitas, Valera, Sue-zette, Dasgupt

Journal:

Leukemia Research

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019

42

Safety and efficacy of oral panobinostat plus chemotherapy in patients aged 65 years or younger with high-risk acute myeloid leukemia

DeAngelo, Daniel J., Walker, Alison R., Schlenk, Richard F., Sierra, Jorge, Medeiros, Bruno C., Ocio, Enrique M., Röllig, Christoph, Strickland, Stephen A., Thol, Felicitas, Valera, Sue-zette, Dasgupt

Journal:

Leukemia Research

Year:

2019

File:

PDF, 1.77 MB

2019

43

Allogeneic stem cell transplantation in patients with myelofibrosis harboring the MPL‐mutation

Mannina, Daniele, Gagelmann, Nico, Badbaran, Anita, Ditschkowski, Markus, Bogdanov, Rashit, Robin, Marie, Cassinat, Bruno, Heuser, Michael, Shahswar, Rabia, Thol, Felicitas, Beelen, Dietrich, Kröger,

Journal:

European Journal of Haematology

Year:

2019

Language:

english

File:

PDF, 381 KB

english, 2019

44

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial

Lübbert, Michael, Grishina, Olga, Schmoor, Claudia, Schlenk, Richard F., Jost, Edgar, Crysandt, Martina, Heuser, Michael, Thol, Felicitas, Salih, Helmut R., Schittenhelm, Marcus M., Germing, Ulrich, K

Journal:

Journal of Clinical Oncology

Year:

2019

File:

PDF, 853 KB

2019

45

Prospective infection surveillance and systematic screening for vancomycin-resistant enterococci in hematologic and oncologic patients â findings of a German tertiary care center

Chhatwal, Patrick, Ebadi, Ella, Thol, Felicitas, Koenecke, Christian, Beutel, Gernot, Ziesing, Stefan, SchlÃ¼ter, Dirk, Bange, Franz-Christoph, Baier, Claas

Journal:

Journal of Global Antimicrobial Resistance

Year:

2020

File:

PDF, 1.51 MB

2020

46

Do next-generation sequencing results drive diagnostic and therapeutic decisions in MDS?

Thol, Felicitas, Platzbecker, Uwe

Journal:

Year:

2019

File:

PDF, 881 KB

2019

47

A Phase II study of selinexor plus cytarabine and idarubicin in patients with relapsed/refractory acute myeloid leukaemia

Fiedler, Walter, Chromik, Joerg, Amberg, Stefanie, Kebenko, Maxim, Thol, Felicitas, Schlipfenbacher, Vera, Christine Wilke, Anne, Modemann, Franziska, Janning, Melanie, Serve, Hubert, Ganser, Arnold,

Journal:

British Journal of Haematology

Year:

2020

File:

PDF, 119 KB

2020

48

Treatment of Relapsed Acute Myeloid Leukemia

Thol, Felicitas, Ganser, Arnold

Journal:

Current Treatment Options in Oncology

Year:

2020

File:

PDF, 274 KB

2020

49

Histiocytic sarcoma progressing from follicular lymphoma and mimicking acquired hemophagocytic lymphohistiocytosis

SchÃ¼nemann, Christoph, GÃ¶hring, Gudrun, Behrens, Yvonne Lisa, Kreipe, Hans-Heinrich, Ganser, Arnold, Thol, Felicitas

Journal:

Annals of Hematology

Year:

2020

File:

PDF, 6.91 MB

2020

50

IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunctionâa retrospective propensity score analysis

Kattih, Badder, Shirvani, Amir, Klement, Piroska, Garrido, Abel Martin, Gabdoulline, Razif, Liebich, Alessandro, Brandes, Maximilian, Chaturvedi, Anuhar, Seeger, Timon, Thol, Felicitas, GÃ¶hring, Gudr

Journal:

Year:

2020

File:

PDF, 1.76 MB

2020